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Synthesis of Aromatic Aldehydes by Oxidative Hydroxymethylation
Journal article   Peer reviewed

Synthesis of Aromatic Aldehydes by Oxidative Hydroxymethylation

O Branytska and Ronny Neumann
Synlett, Vol.2004(9), pp.1575-1576
Jul/2004

Abstract

A new high yield method for the synthesis of aromatic aldehydes has been developed. The procedure is based on an acid catalyzed hydroxymethylation of an arene substrate by paraformaldehyde with concurrent selective oxidation of the intermediate aromatic carbinol by 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) to the aldehyde product.
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