Stress, order and survival

Abraham Minsky; Eyal Shimoni; D Frenkiel-Krispin

doi:10.1038/nrm700

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Journal article

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Stress, order and survival

Abraham Minsky, Eyal Shimoni and D Frenkiel-Krispin

Nature Reviews Molecular Cell Biology, Vol.3(1), pp.50-60

Jan/2002

DOI: https://doi.org/10.1038/nrm700

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Abstract

Much of the sophisticated chemistry of life is accomplished by multicomponent complexes, which act as molecular machines. Intrinsic to their accuracy and efficiency is the energy that is supplied by hydrolysis of nucleoside triphosphates. Conditions that deplete energy sources should therefore cause decay and death. But studies on organisms that are exposed to prolonged stress indicate that this fate could be circumvented through the formation of highly ordered intracellular assemblies. In these thermodynamically stable structures, vital components are protected by a physical sequestration that is independent of energy consumption.

Details

Title: Stress, order and survival
Creators: Abraham Minsky (null) - 972WIS_INST___9
Eyal Shimoni (null) - 972WIS_INST___100
D Frenkiel-Krispin (null)
Resource Type: Journal article; Review
Publication Details: Nature Reviews Molecular Cell Biology, Vol.3(1), pp.50-60; Jan/2002
Number of pages: 11
Language: English
DOI: https://doi.org/10.1038/nrm700
Record Identifier: 993267287803596

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