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Selective hydrogenation of nitriles to primary amines catalyzed by a novel iron complex
Journal article   an open version is available  Peer reviewed

Selective hydrogenation of nitriles to primary amines catalyzed by a novel iron complex

Subrata Chakraborty, Gregory Leitus and David Milstein
Chemical Communications, Vol.52(9), pp.1812-1815
Jan/2016
url
https://doi.org/10.1039/c5cc08204hView
Published (Version of record) Open Access

Abstract

Hydrogenation of nitriles to primary amines constitutes an atom-efficient and environmentally benign synthetic reaction. Herein we present a novel complex based on earth-abundant iron, and its application in the catalytic homogeneous hydrogenation of (hetero)aromatic, benzylic, and aliphatic nitriles to selectively form primary amines.

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