Journal article
New Insights into the Shikimate and Aromatic Amino Acids Biosynthesis Pathways in Plants
Molecular Plant, Vol.3(6), pp.956-972
Nov/2010
Abstract
The aromatic amino acids phenylalanine, tyrosine, and tryptophan in plants are not only essential components of protein synthesis, but also serve as precursors for a wide range of secondary metabolites that are important for plant growth as well as for human nutrition and health. The aromatic amino acids are synthesized via the shikimate pathway followed by the branched aromatic amino acids biosynthesis pathway, with chorismate serving as a major intermediate branch point metabolite. Yet, the regulation and coordination of synthesis of these amino acids are still far from being understood. Recent studies on these pathways identified a number of alternative cross-regulated biosynthesis routes with unique evolutionary origins. Although the major route of Phe and Tyr biosynthesis in plants occurs via the intermediate metabolite arogenate, recent studies suggest that plants can also synthesize phenylalanine via the intermediate metabolite phenylpyruvate (PPY), similarly to many microorganisms. Recent studies also identified a number of transcription factors regulating the expression of genes encoding enzymes of the shikimate and aromatic amino acids pathways as well as of multiple secondary metabolites derived from them in Arabidopsis and in other plant species.
Details
- Title
- New Insights into the Shikimate and Aromatic Amino Acids Biosynthesis Pathways in Plants
- Creators
- Vered Tzin (null)Gad Galili (null) - 972WIS_INST___110
- Resource Type
- Journal article; Review
- Publication Details
- Molecular Plant, Vol.3(6), pp.956-972; Nov/2010
- Number of pages
- 17
- Language
- English
- DOI
- https://doi.org/10.1093/mp/ssq048
- Grant note
- Israeli Ministry of Industry, Trade and Labor; HAZERA GENETICS Ltd.; Evogene Ltd.; FRUTAROM Ltd.; RAHAN MERISTEM Ltd.; ZERAIM GEDERA Ltd.; Israeli Bio-TOV ConsortiumThis Study was supported by a Magnet Program of the Israeli Ministry of Industry, Trade and Labor and the Israeli Bio-TOV Consortium including HAZERA GENETICS Ltd., Evogene Ltd., FRUTAROM Ltd., RAHAN MERISTEM (1998) Ltd. and ZERAIM GEDERA Ltd. No conflict of interest declared._ALMAME_DELIMITER_
- Record Identifier
- 993267296303596
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