Journal article
Metal-Ligand Cooperation
Angewandte Chemie - International Edition, Vol.54(42), pp.12236-12273
2015
Abstract
Metal-ligand cooperation (MLC) has become an important concept in catalysis by transition metal complexes both in synthetic and biological systems. MLC implies that both the metal and the ligand are directly involved in bond activation processes, by contrast to "classical" transition metal catalysis where the ligand (e.g. phosphine) acts as a spectator, while all key transformations occur at the metal center. In this Review, we will discuss examples of MLC in which 1) both the metal and the ligand are chemically modified during bond activation and 2) bond activation results in immediate changes in the 1st coordination sphere involving the cooperating ligand, even if the reactive center at the ligand is not directly bound to the metal (e.g. via tautomerization). The role of MLC in enabling effective catalysis as well as in catalyst deactivation reactions will be discussed. Together we're effective: Metal-ligand cooperation (MLC) implies that both the metal and the ligand are directly involved in bond activation processes, in contrast to "classical" transition metal catalysis where the ligand acts as a spectator, while all key transformations occur at the metal center. This Review discusses diverse modes of MLC in bond formation and bond cleavage reactions. 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Details
- Title
- Metal-Ligand Cooperation
- Creators
- J.R. Khusnutdinova (null)David Milstein (null) - The Weizmann Institute of Science
- Resource Type
- Journal article
- Publication Details
- Angewandte Chemie - International Edition, Vol.54(42), pp.12236-12273; 2015
- Language
- English
- DOI
- https://doi.org/10.1002/anie.201503873
- Record Identifier
- 993264852603596
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