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Increased para Selectivity in the Reimer-Tiemann Reaction by Use of Polyethylene Glycol as Complexing Agent
Journal article   Peer reviewed

Increased para Selectivity in the Reimer-Tiemann Reaction by Use of Polyethylene Glycol as Complexing Agent

Ronny Neumann and Yoel Sasson
Synthesis (Stuttgart), Vol.1986(7), pp.569-570
Jul/1986

Abstract

The para selectivity of the Reimer-Tiemann reaction was increased by use of polyethylene glycol in the reaction medium. The polyethylene glycol complexes the phenolate substrate masking the ortho position of the benzene nucleus increasing para selectivity without affecting the total yield.
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