Journal article
Cracking the epitranscriptome.
RNA, Vol.22(2), pp.169-174
Feb/2016
Abstract
Over 100 distinct chemical modifications can be catalyzed on RNA post-synthesis, potentially serving as a post-transcriptional regulatory layer of gene expression. This review focuses on recent advances, knowledge gaps, and challenges pertaining to N6-methyladenosine (m6A), an abundant modification of mRNA for which substantial progress has been made in recent years. The discussed aspects are also very relevant for a wide range of additional modifications on mRNA collectively coined the epitranscriptome.
Details
- Title
- Cracking the epitranscriptome.
- Creators
- Schraga Schwartz (null) - 972WIS_INST___111
- Resource Type
- Journal article; Review
- Publication Details
- RNA, Vol.22(2), pp.169-174; Feb/2016
- Number of pages
- 6
- Language
- English
- DOI
- https://doi.org/10.1261/rna.054502.115
- Grant note
- Abramson Family Center; David and Fela Shapell Family Foundation INCPM Fund for Preclinical Studies S.S. is supported by research grants from the Abramson Family Center for Young Scientists, the David and Fela Shapell Family Foundation INCPM Fund for Preclinical Studies, and the Estate of David Turner._ALMAME_DELIMITER_
- Record Identifier
- 993266320403596
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