Editorial material
Toward More Transparent and Reproducible Omics Studies Through a Common Metadata Checklist and Data Publications
Omics-A Journal Of Integrative Biology, Vol.18(1), pp.10-14
Jan/2014
Abstract
Biological processes are fundamentally driven by complex interactions between biomolecules. Integrated high-throughput omics studies enable multifaceted views of cells, organisms, or their communities. With the advent of new post-genomics technologies, omics studies are becoming increasingly prevalent; yet the full impact of these studies can only be realized through data harmonization, sharing, meta-analysis, and integrated research. These essential steps require consistent generation, capture, and distribution of metadata. To ensure transparency, facilitate data harmonization, and maximize reproducibility and usability of life sciences studies, we propose a simple common omics metadata checklist. The proposed checklist is built on the rich ontologies and standards already in use by the life sciences community. The checklist will serve as a common denominator to guide experimental design, capture important parameters, and be used as a standard format for stand-alone data publications. The omics metadata checklist and data publications will create efficient linkages between omics data and knowledge-based life sciences innovation and, importantly, allow for appropriate attribution to data generators and infrastructure science builders in the post-genomics era. We ask that the life sciences community test the proposed omics metadata checklist and data publications and provide feedback for their use and improvement.
Details
- Title
- Toward More Transparent and Reproducible Omics Studies Through a Common Metadata Checklist and Data Publications
- Creators
- Eugene Kolker (null)Vural Ozdemir (null)Lennart Martens (null)William Hancock (null)Gordon Anderson (null)Nathaniel Anderson (null)Sukru Aynacioglu (null)Ancha Baranova (null)Shawn R. Campagna (null)Rui Chen (null)John Choiniere (null)Stephen P. Dearth (null)Wu-Chun Feng (null)Lynnette Ferguson (null)Geoffrey Fox (null)Dmitrij Frishman (null)Robert Grossman (null)Allison Heath (null)Roger Higdon (null)
- Resource Type
- Editorial material
- Publication Details
- Omics-A Journal Of Integrative Biology, Vol.18(1), pp.10-14; Jan/2014
- Number of pages
- 5
- Language
- English
- DOI
- https://doi.org/10.1089/omi.2013.0149
- Scientific Unit
- The Weizmann Institute of Science
- Record Identifier
- 993262051903596
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