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Huntingtin facilitates selective autophagy
Editorial material   Peer reviewed

Huntingtin facilitates selective autophagy

Amir Gelman, Slobodkin, Moran Rawet Slobodkin and Zvulun Elazar
Nature Cell Biology, Vol.17(3), pp.214-215
Mar/2015
url
https://doi.org/10.1038/ncb3125View
Published (Version of record) Restricted

Abstract

Selective autophagy is essential for maintaining cellular homeostasis under different growth conditions. Huntingtin, mutated versions of which have been implicated in Huntington disease, is now shown to act as a scaffold protein that couples the induction of autophagy and the selective recruitment of cargo into autophagosomes.

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